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For example, some dynamic composite polymer networks display the properties of a mechanical machine. Throughout the study of these complex networks we hope to identify some general physical aspects of biological organization.
This research offers interdisciplinary training opportunities for individuals with either a biological or physical sciences background. Techniques involved in biophysics depend on the expertise of non-linear dynamics, computational biology, lasers, time-resolved fluorescence, confocal microscopy, protein-engineering, signal transduction, gene expression, mathematical modeling, large-scale simulations, stochastic and self-assembly processes, optical and holographic traps, single-molecule biophysics.
Almost every area of modern biology, from molecular genetics to neuroscience, is being revolutionized by large scale, quantitative experiments and sophisticated theoretical analyses. From observing the dynamics of single biological molecules to building theories of neural networks, there are myriad challenges for physicists and biologists willing to explore the boundary between their disciplines. Our work is animated by the belief that, as in other areas of physics, the striking qualitative phenomena of life should have correspondingly deep theoretical explanations, and that this understanding ultimately will be tested only by a new generation of quantitative experiments.
Princeton University offers a unique environment for research and education at the interface between physics and biology.
More than 25 faculty and fellows are currently engaged in biological physics research across campus. Barriers between departments are low, and are reduced by multidisciplinary initiatives such as the Lewis-Sigler Institute , the Princeton Neuroscience Institute , graduate programs in Quantitative and Computational Biology and Neuroscience , and the Biophysics certificate program for undergraduates. Specific areas of focus include: antibody-antigen binding; tissue engineering; controlled local gene delivery; biomaterials development. Biocomputing Our biocomputing research focuses on discovering new ways to analyse and interpret experimental data and relate it to the functions of life.
Through our research, we look to address the following questions: How do we interpret, analyse the experimental information and relate it to the functions of life? Can we reconstruct biological systems from such detailed information?
stanfidebotra.tk Biomolecular structure and dynamics Research in this field includes the study of water around DNA, proteins and biopolymers using various neutron sources around the world. Intracellular particle tracking and self-assembly We are examining a number of new microrheology methods to examine the viscoelasticity inside live cells and relate these properties to the structure and dynamics of the constituent cellular biomolecules. Our research Explore the wider research themes, centres and facilities in the Department of Physics and Astronomy.
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